Far-UVC (222nm) Research

At DynaKleen, we believe Far-UVC will soon become the standard of clean in medical facilities. Below we have complied some of the peer-reviewed research that supports this cutting-edge technology.

  1. Further evidence that far‐UVC for disinfection is unlikely to cause erythema or pre‐mutagenic DNA lesions in skin

    Barnard, I., Eadie, E., & Wood, K. (2020). Further evidence that far-UVC for disinfection is unlikely to cause erythema or pre-mutagenic DNA lesions in skin. Photodermatology, photoimmunology & photomedicine, 10.1111/phpp.12580. Advance online publication. https://doi.org/10.1111/phpp.12580

  2. Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light

    Buonanno, M., Ponnaiya, B., Welch, D., Stanislauskas, M., Randers-Pehrson, G., Smilenov, L., Lowy, F. D., Owens, D. M., & Brenner, D. J. (2017). Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light. Radiation research, 187(4), 483–491. https://doi.org/10.1667/RR0010CC.1

  3. 207-nm UV light - a promising tool for safe low-cost reduction of surgical site infections. I: in vitro studies

    Buonanno, M., Randers-Pehrson, G., Bigelow, A. W., Trivedi, S., Lowy, F. D., Spotnitz, H. M., Hammer, S. M., & Brenner, D. J. (2013). 207-nm UV light - a promising tool for safe low-cost reduction of surgical site infections. I: in vitro studies. PloS one, 8(10), e76968. https://doi.org/10.1371/journal.pone.0076968

  4. 207-nm UV Light-A Promising Tool for Safe Low-Cost Reduction of Surgical Site Infections. II: In-Vivo Safety Studies

    Buonanno, M., Stanislauskas, M., Ponnaiya, B., Bigelow, A. W., Randers-Pehrson, G., Xu, Y., Shuryak, I., Smilenov, L., Owens, D. M., & Brenner, D. J. (2016). 207-nm UV Light-A Promising Tool for Safe Low-Cost Reduction of Surgical Site Infections. II: In-Vivo Safety Studies. PloS one, 11(6), e0138418. https://doi.org/10.1371/journal.pone.0138418

  5. Extreme Exposure to Filtered Far-UVC: A Case Study

    Eadie, Ewan & Barnard, Isla & Ibbotson, Sally & Wood, Kenneth. (2020). Extreme Exposure to Filtered Far-UVC: A Case Study. 10.13140/RG.2.2.20204.18568.

  6. Exploratory clinical trial on the safety and bactericidal effect of 222-nm ultraviolet C irradiation in healthy humans

    Fukui T, Niikura T, Oda T, et al. Exploratory clinical trial on the safety and bactericidal effect of 222-nm ultraviolet C irradiation in healthy humans. Plos one. 2020 ;15(8):e0235948. DOI: 10.1371/journal.pone.0235948.

  7. Evaluation of acute corneal damage induced by 222-nm and 254-nm ultraviolet light in Sprague-Dawley rats

    Kaidzu S, Sugihara K, Sasaki M, Nishiaki A, Igarashi T, Tanito M. Evaluation of acute corneal damage induced by 222-nm and 254-nm ultraviolet light in Sprague-Dawley rats. Free Radic Res. 2019 Jun;53(6):611-617. doi: 10.1080/10715762.2019.1603378. Epub 2019 May 27. PMID: 30947566.

  8. Chronic irradiation with 222-nm UVC light induces neither DNA damage nor epidermal lesions in mouse skin, even at high doses

    Narita K, Asano K, Morimoto Y, Igarashi T, Nakane A (2018) Chronic irradiation with 222-nm UVC light induces neither DNA damage nor epidermal lesions in mouse skin, even at high doses. PLoS ONE 13(7): e0201259. https://doi.org/10.1371/journal.pone.0201259

  9. Disinfection and healing effects of 222-nm UVC light on methicillin-resistant Staphylococcus aureus infection in mouse wounds

    Narita K, Asano K, Morimoto Y, et al. Disinfection and healing effects of 222-nm UVC light on methicillin-resistant Staphylococcus aureus infection in mouse wounds [published correction appears in J Photochem Photobiol B. 2018 Apr 3;:]. J Photochem Photobiol B. 2018;178:10-18. doi:10.1016/j.jphotobiol.2017.10.030

  10. Far-UVC light prevents MRSA infection of superficial wounds in vivo

    Ponnaiya B, Buonanno M, Welch D, Shuryak I, Randers-Pehrson G, Brenner DJ (2018) Far-UVC light prevents MRSA infection of superficial wounds in vivo. PLoS ONE 13(2): e0192053. https://doi.org/10.1371/journal.pone.0192053

  11. Long-term Effects of 222-nm ultraviolet radiation C Sterilizing Lamps on Mice Susceptible to Ultraviolet Radiation

    Yamano, N., Kunisada, M., Kaidzu, S., Sugihara, K., Nishiaki-Sawada, A., Ohashi, H., Yoshioka, A., Igarashi, T., Ohira, A., Tanito, M., & Nishigori, C. (2020). Long-term Effects of 222-nm ultraviolet radiation C Sterilizing Lamps on Mice Susceptible to Ultraviolet Radiation. Photochemistry and photobiology, 96(4), 853–862. https://doi.org/10.1111/php.13269